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Drugs in development · updated 30 October 2026

Anophthalmia with pulmonary hypoplasia: drugs in development

As of 30 October 2026 there are 5 active clinical trials (recruiting or ongoing, phases I–III) on 11 drugs for anophthalmia with pulmonary hypoplasia. 6 are experimental, that is not yet approved in the United States.

5Active trials
6Experimental drugs
0Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
HLX22II1NCT07176702
SurufatinibSulfatinib, Sevsury®II1NCT06361030
AzirkitugI1NCT05005403
BudigalimabABBV-181I1NCT05005403
DSB2455I1NCT06458712
Telisotuzumab AdizutecanI1NCT05005403

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
GemcitabineGemcitabin, GemzarII2NCT06361030
Nab-paclitaxelAbraxane, Nab-placlitaxelII2NCT06361030
TrastuzumabHerceptin, tratuzumabII1NCT07176702
Bevacizumabavastin, MVASII1NCT05005403
MIRALAXPEG 3350, Polyethylene Glycol 3350I1NCT06393400

Sorted by most advanced phase and number of active trials.

All 11 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: NLM MeSH; NLM MeSH term: C537768 “Anophthalmia with pulmonary hypoplasia”.

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