Phuturdex › Diseases › Digital ulcer
Drugs in development · updated 9 November 2026
Digital ulcer: drugs in development
What it is
Necrotic lesions located at distal digits of fingers and toes in humans. Differentiate with DIGITAL DERMATITIS, an infection of the interdigital spaces commonly found in bovine.
Source: NLM MeSH (U.S. National Library of Medicine), descriptor C000721267, meshb.nlm.nih.gov · public domain · downloaded on 9 November 2026.
As of 9 November 2026 there are 2 active clinical trials (recruiting or ongoing, phases I–III) on 3 drugs for digital ulcer. 2 are experimental, that is not yet approved in the United States.
Summary updated every week · data as of 9 November 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.
Sign in free →Experimental drugs
Not yet approved by the US FDA for any indication.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| L608 | II | 1 | NCT07925619 |
| TOP-N53 | II | 1 | NCT06954597 |
Sorted by most advanced phase and number of active trials.
Approved drugs in new trials
Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| SildenafilViagra, Liqrev® | II | 1 | NCT06954597 |
Sorted by most advanced phase and number of active trials.
All 3 drugs, with the details
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Open in Phuturdex →Broader categories
- Skin disease 1,366 drugs
- Skin and connective tissue diseases 1,526 drugs
- Connective tissue disease 357 drugs
Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 9 November 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: C000721267 “digital ulcers”.