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Drugs in development · updated 30 October 2026

Disorder of consciousness: drugs in development

As of 30 October 2026 there are 3 active clinical trials (recruiting or ongoing, phases I–III) on 3 drugs for disorder of consciousness. One is experimental, that is not yet approved in the United States.

3Active trials
1Experimental drugs
1Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
PhosphocreatineIII1NCT06503016

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
Apomorphine infusionOnapgo®, Kynmobi®II–III1NCT05213169
MethylphenidateConcerta, Relexxii®I1NCT03814356

Sorted by most advanced phase and number of active trials.

All 3 drugs, with the details

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Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D003244 “Consciousness Disorders”.

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