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Drugs in development · updated 30 October 2026

Eosinophilic esophagitis: drugs in development

As of 30 October 2026 there are 10 active clinical trials (recruiting or ongoing, phases I–III) on 8 drugs for eosinophilic esophagitis. 2 are experimental, that is not yet approved in the United States.

10Active trials
2Experimental drugs
0Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
EP-104GII–II1NCT05608681
SolrikitugII1NCT06598462

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
DupilumabDUPIXENTIII4NCT07112378
BudesonideTarpeyo®, Eohilia®III2NCT06596252
TezepelumabTezspireIII1NCT05583227
Fluticasone PropionateFluticasone, Xhance®II1NCT06705387
UpadacitinibRinvoq Lq®, Rinvoq®II1NCT07588568
VonoprazanVonoparazan, Voquezna®II1NCT06851559

Sorted by most advanced phase and number of active trials.

All 8 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D057765 “Eosinophilic Esophagitis”.

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