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Drugs in development · updated 30 October 2026

Gastro-enteropancreatic neuroendocrine tumor: drugs in development

As of 30 October 2026 there are 16 active clinical trials (recruiting or ongoing, phases I–III) on 22 drugs for gastro-enteropancreatic neuroendocrine tumor. 10 are experimental, that is not yet approved in the United States.

16Active trials
10Experimental drugs
2Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
CAM2029III1NCT05050942
RYZ101III1NCT05477576
CVM-1118II1NCT03600233
DomvanalimabAB154II1NCT06790706
DotatateII1NCT04711135
ESK981II1NCT05988918
ZimberelimabAB122, GLS-010II1NCT06790706
177Lu-DOTATOCLutetium Lu 177-EdotreotideI1NCT06441331
E7386I1NCT03833700
RYZ401I1NCT07165132

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
LutatheraLutetium Lu 177 Dotatate, 177Lu-DOTATATEIII4NCT03972488
EverolimusRAD001, EveroliumusIII2NCT05477576
TemozolomideTemodal, TemodarIII2NCT04919226
Fluorouracil5-Fluorouracil, AdrucilIII1NCT04919226
LanreotideSomatuline Depot®III1NCT05477576
OctreotideSandostatin LAR@, Bynfezia Pen®III1NCT05477576
OxaliplatinOxaliplatine, OxaliplainIII1NCT04919226
SunitinibSutent®, Sunitinib Accord®III1NCT05477576
AbemaciclibLY2835219, Verzenio®II1NCT03891784
CabozantinibResniben®, Cabometyx®II1NCT04893785
CarboplatinCarboplatine, ParaplatinI–II1NCT05385861
68Ga-DOTATATEGallium 68 Dotatate, Gallium Ga 68-DOTATATEI1NCT04609592

Sorted by most advanced phase and number of active trials.

All 22 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: NLM MeSH; NLM MeSH term: C535650 “Gastro-enteropancreatic neuroendocrine tumor”.

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