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Drugs in development · updated 30 October 2026

Pulmonary embolism: drugs in development

As of 30 October 2026 there are 14 active clinical trials (recruiting or ongoing, phases I–III) on 11 drugs for pulmonary embolism. 6 are experimental, that is not yet approved in the United States.

14Active trials
6Experimental drugs
4Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
CenvacibartREGN7508III4NCT07213778
AntiplateletIII1NCT05627375
KinisoquinIII1NCT06861088
REGN9933III1NCT07430956
TS23II1NCT05408546
VortosiranII1NCT07850453

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
AlteplaseActivase®, Cathflo Activase®III2NCT04430569
ApixabanEliquis, Abanta®III2NCT07493304
AspirinVazalore®, Durlaza®III1NCT06494878
HeparinUnfractionated heparin, Heparin Sodium Preservative Free®III1NCT06453876
RivaroxabanRivoroxaban, Yulzety®III1NCT06195540

Sorted by most advanced phase and number of active trials.

All 11 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D011655 “Pulmonary Embolism”.

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