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Drugs in development · updated 30 October 2026

Buprenorphine: clinical trials and development status

Other names and codes: Brixadi, Sublocade, Belbuca, Probuphine

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 26 September 2006

As of 30 October 2026 Buprenorphine is in 15 active clinical trials (recruiting or ongoing, phases I–III) for 6 diseases. The most advanced phase is III.

15Active trials
IIIMost advanced phase
6Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Buprenorphine and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Opioid-related disordersIII11NCT05589181
DepressionIII1NCT03646058
Suicidal ideationIII1NCT03646058
Chronic painI–II1NCT06442566
Fractures, BoneI–II1NCT07430345
SchizophreniaII1NCT05778591

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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