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Drugs in development · updated 30 October 2026

CDK4: clinical trials and development status

FDA substance registryNot approved in the USNo EMA authorisationEstimated launch Dec 2027 – Oct 2028 (Phuturdex estimate)

As of 30 October 2026 CDK4 is in 29 active clinical trials (recruiting or ongoing, phases I–III) for 4 diseases. The most advanced phase is III.

29Active trials
IIIMost advanced phase
4Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow CDK4 and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Breast neoplasmIII20NCT06790693
MetastasisIII1NCT07802626
Salivary gland neoplasmII1NCT06145308
MedulloblastomaEarly I1NCT06959979

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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