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Drugs in development · updated 30 October 2026

Metreleptin: clinical trials and development status

Other names and codes: Myalept

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 30 July 2018

As of 30 October 2026 Metreleptin is in 7 active clinical trials (recruiting or ongoing, phases I–III) for 12 diseases. The most advanced phase is III.

7Active trials
IIIMost advanced phase
12Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Metreleptin and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
DiabetesIII2NCT02262832
HyperlipidemiaIII2NCT02262832
HypertriglyceridemiaIII2NCT02262832
LipodystrophyIII2NCT02262832
Familial partial lipodystrophyIII1NCT06679270
Lipodystrophy, Partial, AcquiredIII1NCT05164341
Anorexia nervosaII1NCT06305182
DepressionII1NCT06305182
Diabetes Mellitus, Insulin-Resistant, with Acanthosis NigricansII1NCT00085982
Insulin resistanceII1NCT00085982
Multiple symmetric lipomatosisII1NCT05351164
Weight gainII1NCT06305182

Everything on Metreleptin

In Phuturdex you get every trial with sponsors, countries and dates, development events, FDA and EMA approvals, patents and exclusivities, orphan designations and safety alerts, with PDF and Excel export. Free until 31 March 2027.

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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