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Drugs in development · updated 30 October 2026

Nalmefene: clinical trials and development status

Other names and codes: Zurnai (Autoinjector), Opvee, Revex, Selincro

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 24 February 2013

As of 30 October 2026 Nalmefene is in 3 active clinical trials (recruiting or ongoing, phases I–III) for 6 diseases. The most advanced phase is III.

3Active trials
IIIMost advanced phase
6Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Nalmefene and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Compulsive sexual behaviour disorderIII1NCT05540288
Food addictionIII1NCT05540288
GamblingIII1NCT05540288
Liver Cirrhosis, BiliaryII1NCT06733519
PruritusII1NCT06733519
Opioid-related disordersI1NCT07325279

Everything on Nalmefene

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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