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Drugs in development · updated 30 October 2026

Ponatinib: clinical trials and development status

Other names and codes: Iclusig

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 1 July 2013

As of 30 October 2026 Ponatinib is in 18 active clinical trials (recruiting or ongoing, phases I–III) for 11 diseases. The most advanced phase is III.

18Active trials
IIIMost advanced phase
11Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Ponatinib and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Precursor lymphoblastic lymphoma/leukemiaIII11NCT04722848
Accelerated phase chronic myelogenous leukemiaII4NCT01424982
Blast CrisisII4NCT01424982
Chronic phase chronic myelogenous leukemiaII2NCT01746836
LeukemiaII2NCT04747912
Leukemia, Myelogenous, Chronic, BCR-ABL PositiveII2NCT01746836
Acute myeloid leukemiaI–II1NCT03934372
Burkitt lymphomaII1NCT03739814
CarcinomaII1NCT06813079
LymphomaI–II1NCT03934372
Pancreatic ductal carcinomaII1NCT06813079

Everything on Ponatinib

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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