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Drugs in development · updated 30 October 2026

Pralatrexate: clinical trials and development status

Other names and codes: 10-propargyl-10-deazaaminopterin, Folotyn

NLM verified identityApproved in the US (FDA)

As of 30 October 2026 Pralatrexate is in 10 active clinical trials (recruiting or ongoing, phases I–III) for 10 diseases. The most advanced phase is III.

10Active trials
IIIMost advanced phase
10Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Pralatrexate and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
T-cell lymphomaIII6NCT06561048
Anaplastic large-cell lymphomaIII3NCT06561048
Peripheral T-cell lymphomaIII3NCT06072131
Immunoblastic lymphadenopathyIII2NCT06561048
Enteropathy-associated T-cell lymphomaI–II2NCT03598998
Subcutaneous T-cell lymphomaI–II2NCT03598998
Follicular lymphomaI–II1NCT03598998
Mycosis fungoidesI–II1NCT03598998
Hematologic neoplasmI1NCT07036133
Leukemia, Large Granular LymphocyticEarly I1NCT03719105

Everything on Pralatrexate

In Phuturdex you get every trial with sponsors, countries and dates, development events, FDA and EMA approvals, patents and exclusivities, orphan designations and safety alerts, with PDF and Excel export. Free until 31 March 2027.

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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