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Drugs in development · updated 30 October 2026

Adjustment disorder: drugs in development

As of 30 October 2026 there are 4 active clinical trials (recruiting or ongoing, phases I–III) on 3 drugs for adjustment disorder. 3 are experimental, that is not yet approved in the United States.

4Active trials
3Experimental drugs
0Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
MDMA3,4-Methylenedioxymethamphetamine, Midomafetamine HClII2NCT05455996
PsilocybinPsilocybineII1NCT07072728
RE104 for InjectionII1NCT07002034

Sorted by most advanced phase and number of active trials.

All 3 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D000275 “Adjustment Disorders”.

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