PhuturdexDrug Pipeline Intelligence

Phuturdex › Drugs › Psilocybin

Drugs in development · updated 30 October 2026

Psilocybin: clinical trials and development status

NLM verified identityNot approved in the USNo EMA authorisationEstimated launch Dec 2027 – Oct 2028 (Phuturdex estimate)

As of 30 October 2026 Psilocybin is in 148 active clinical trials (recruiting or ongoing, phases I–III) for 80 diseases. The most advanced phase is III.

148Active trials
IIIMost advanced phase
80Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Psilocybin and get an email at every change or safety alert.

Sign in free →

Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 80 diseases.

DiseaseMost advanced phaseActive trialsReference trial
DepressionIII31NCT07226232
Major depressive disorderIII17NCT07226232
Depressive Disorder, Treatment-ResistantIII14NCT05711940
Post-traumatic stress disorderIII13NCT07226232
AlcoholismIII10NCT07638553
Wounds and InjuriesIII2NCT07703722
Anxiety disorderII7NCT07336238
Opioid-related disordersII7NCT06001749
Chronic painII5NCT06518720
Substance-related disorderII5NCT07774702
Bipolar disorderII4NCT06943573
NeoplasmII4NCT07072728
Obsessive-compulsive disorderI–II4NCT06992999
Depressive disorderII3NCT07216404
MelanomaII3NCT07072728
Suicidal ideationII3NCT07745569
Alzheimer's diseaseII2NCT07721467
Amphetamine-related disordersII2NCT07756736
Amyotrophic lateral sclerosisII2NCT06782724
Anorexia nervosaII2NCT07169747
Breast neoplasmII2NCT07072728
Combat disorderII2NCT07745569
Endocrine gland neoplasmII2NCT07820033
LymphomaII2NCT07820033
Mood disorderII2NCT06943573
Movement disordersII2NCT07610369
NeuralgiaII2NCT06731335
Parkinson's diseaseII2NCT07610369
Tobacco use disorderII2NCT07852832
Well-beingII2NCT06233344

Everything on Psilocybin

In Phuturdex you get every trial with sponsors, countries and dates, development events, FDA and EMA approvals, patents and exclusivities, orphan designations and safety alerts, with PDF and Excel export. Free until 31 March 2027.

Open in Phuturdex →

Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

ItalianoFrançaisDeutsch