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Phuturdex › Diseases › Blastic plasmacytoid dendritic cell neoplasm

Drugs in development · updated 30 October 2026

Blastic plasmacytoid dendritic cell neoplasm: drugs in development

As of 30 October 2026 there are 12 active clinical trials (recruiting or ongoing, phases I–III) on 24 drugs for blastic plasmacytoid dendritic cell neoplasm. 2 are experimental, that is not yet approved in the United States.

12Active trials
2Experimental drugs
0Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
MGD024I1NCT05362773
SENTI-202I1NCT06325748

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
CyclophosphamideCyclophosphamid, CytoxanII6NCT06013423
FludarabineFludara, FLUDARABINII6NCT06013423
TagraxofuspTagraxofusp-erzs, SL-401II4NCT04216524
MethotrexateJylamvo®, Reditrex®II3NCT03779854
VenetoclaxVentoclax, Venclexta®II3NCT04216524
CytarabineAra-C, Cytosine ArabinosideII2NCT04216524
DexamethasoneDexametasone, DextenzaII2NCT04216524
RituximabRuxience, RituxanII2NCT04216524
ThiotepaTepylute®, Tepadina And Sodium Chloride®II2NCT06013423
VincristineVincristin, Oncovin [vincristine]II2NCT04216524
BusulfanBusulphan, Busulfex®II1NCT03779854
CyclosporineCyclosporine A, Cyclosporin CapsulesII1NCT06013423
DoxorubicinAdriamycin, DoxorubincinII1NCT04216524
Mercaptopurine6-Mercaptopurine, MecaptopurineII1NCT04216524
MethylprednisoloneMethylprednisolon, MethylprenisoloneII1NCT04216524

Sorted by most advanced phase and number of active trials. Showing 15 of 22 drugs.

All 24 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D000099067 “Blastic Plasmacytoid Dendritic Cell Neoplasm”.

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