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Drugs in development · updated 30 October 2026

Thiotepa: clinical trials and development status

Other names and codes: Tepylute, Tepadina And Sodium Chloride, Tepadina, Thioplex

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 15 March 2010

As of 30 October 2026 Thiotepa is in 58 active clinical trials (recruiting or ongoing, phases I–III) for 80 diseases. The most advanced phase is III.

58Active trials
IIIMost advanced phase
80Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Thiotepa and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 80 diseases.

DiseaseMost advanced phaseActive trialsReference trial
Acute myeloid leukemiaIII14NCT05457556
Myelodysplastic SyndromesIII14NCT05457556
Precursor lymphoblastic lymphoma/leukemiaIII14NCT05457556
NeuroblastomaIII5NCT06172296
Acute biphenotypic leukaemiaIII4NCT05457556
Breast neoplasmIII2NCT01646034
GanglioneuroblastomaIII2NCT06172296
Chronic myelomonocytic leukemiaII–III1NCT04708054
Hematologic neoplasmII7NCT02861417
Non-Hodgkin lymphomaII7NCT06013423
Leukemia, Myelogenous, Chronic, BCR-ABL PositiveII6NCT06013423
Graft-versus-host diseaseII5NCT07566377
Myeloproliferative disordersII5NCT06013423
Sickle-cell diseaseII4NCT04362293
Hodgkin lymphomaII3NCT03849651
Multiple myelomaII3NCT02861417
Beta thalassemiaII2NCT01962415
Blastic plasmacytoid dendritic cell neoplasmII2NCT06013423
Burkitt lymphomaII2NCT03779854
Crohn's diseaseII2NCT01962415
Diamond-Blackfan anemiaII2NCT01962415
GlioblastomaII2NCT07511725
Juvenile myelomonocytic leukemiaII2NCT03849651
LeukemiaII2NCT07566377
Meningeal carcinomatosisII2NCT07778940
Severe combined immunodeficiencyII2NCT01962415
Acute monocytic leukemiaII1NCT03970096
AdrenoleukodystrophyII1NCT01962415
Alpha-mannosidosisII1NCT01962415
AnemiaI–II1NCT03653338

Everything on Thiotepa

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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