Phuturdex › Diseases › Bone disease
Drugs in development · updated 30 October 2026
Bone disease: drugs in development
As of 30 October 2026 there are 15 active clinical trials (recruiting or ongoing, phases I–III) on 9 drugs for bone disease. 3 are experimental, that is not yet approved in the United States.
Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.
Sign in free →Experimental drugs
Not yet approved by the US FDA for any indication.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| BMN 333 | II–III | 1 | NCT07441876 |
| Narlumosbart | III | 1 | NCT06314698 |
| KK8123 | I–II | 1 | NCT06525636 |
Sorted by most advanced phase and number of active trials.
Approved drugs in new trials
Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| VosoritideBMN 111, Voxzogo® | II–III | 6 | NCT07441876 |
| InfigratinibTruseltiq®, Febseltiq® | II–III | 4 | NCT06873035 |
| DenosumabProlia, Degevma® | III | 2 | NCT06314698 |
| Autologous cultured chondrocytes on porcine collagen membrane | III | 1 | NCT06915233 |
| FinasteridePropecia®, Proscar® | II–III | 1 | NCT07742553 |
| Testosterone cypionateAzmiro® | II–III | 1 | NCT07742553 |
Sorted by most advanced phase and number of active trials.
All 9 drugs, with the details
In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.
Open in Phuturdex →Specific forms
- Psoriatic arthritis 48 drugs
- Bone neoplasm 25 drugs
- Dwarfism, Pituitary 6 drugs
- Osteoporosis 10 drugs
- Sarcoma 204 drugs
- Osteosarcoma 101 drugs
- Achondroplasia 8 drugs
- Axial spondyloarthritis 5 drugs
- Osteogenesis imperfecta 4 drugs
- Rheumatoid arthritis 130 drugs
- Ankylosing spondylitis 31 drugs
- Metabolic bone disease 4 drugs
Broader categories
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities 4 drugs
- Endocrine system disease 19 drugs
- Skin and connective tissue diseases 3 drugs
- Nutritional and metabolic diseases 5 drugs
- Genetic disease 33 drugs
- Metabolism, Inborn Errors 6 drugs
Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D001847 “Bone Diseases”.