Phuturdex › Diseases › DNA repair-deficiency disorder
Drugs in development · updated 30 October 2026
DNA repair-deficiency disorder: drugs in development
As of 30 October 2026 there are 1 active clinical trials (recruiting or ongoing, phases I–III) on 4 drugs for DNA repair-deficiency disorder. 0 are experimental, that is not yet approved in the United States.
Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.
Sign in free →Approved drugs in new trials
Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| AtezolizumabTecentriq, MPDL3280A | III | 1 | NCT02912559 |
| Fluorouracil5-Fluorouracil, Adrucil | III | 1 | NCT02912559 |
| LeucovorinFolinic acid, l-leucovorin | III | 1 | NCT02912559 |
| OxaliplatinOxaliplatine, Oxaliplain | III | 1 | NCT02912559 |
Sorted by most advanced phase and number of active trials.
All 4 drugs, with the details
In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.
Open in Phuturdex →Specific forms
- Fanconi anemia 16 drugs
- Colorectal Neoplasms, Hereditary Nonpolyposis 12 drugs
- Severe combined immunodeficiency 8 drugs
- Dyskeratosis congenita 15 drugs
- Ataxia telangiectasia 3 drugs
- Aplastic anemia 43 drugs
- Myelodysplastic Syndromes 203 drugs
- Bone marrow failure 26 drugs
- Primary immunodeficiency disease 13 drugs
- Graft-versus-host disease 49 drugs
- Wiskott-Aldrich syndrome 7 drugs
- Chronic granulomatous disease 21 drugs
Broader categories
- Neoplasm 671 drugs
- Digestive System Diseases 36 drugs
- Metabolic disease 30 drugs
- Nutritional and metabolic diseases 5 drugs
- Digestive system neoplasm 37 drugs
- Colorectal neoplasm 534 drugs
Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D049914 “DNA Repair-Deficiency Disorders”.