Phuturdex › Diseases › Colorectal neoplasm
Drugs in development · updated 30 October 2026
Colorectal neoplasm: drugs in development
As of 30 October 2026 there are 666 active clinical trials (recruiting or ongoing, phases I–III) on 534 drugs for colorectal neoplasm. 380 are experimental, that is not yet approved in the United States.
Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.
Sign in free →Experimental drugs
Not yet approved by the US FDA for any indication.
Sorted by most advanced phase and number of active trials. Showing 40 of 380 drugs.
Approved drugs in new trials
Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| Bevacizumabavastin, MVASI | II–III | 149 | NCT07221357 |
| CetuximabErbitux | III | 81 | NCT07775287 |
| OxaliplatinOxaliplatine, Oxaliplain | II–III | 73 | NCT06280495 |
| PembrolizumabKEYTRUDA, MK-3475 | III | 64 | NCT07750158 |
| Fluorouracil5-Fluorouracil, Adrucil | II–III | 59 | NCT06280495 |
| IrinotecanOnivyde, CPT-11 | II–III | 54 | NCT07585279 |
| LeucovorinFolinic acid, l-leucovorin | II–III | 54 | NCT05141721 |
| CapecitabineXeloda, Capectitabine Tablets | III | 53 | NCT07885384 |
| FruquintinibFruquinitinib, Fruzaqla® | II–III | 36 | NCT06441565 |
| NivolumabOpdivo, ONO-4538 | III | 29 | NCT07620574 |
| Tipiracil | III | 26 | NCT07525206 |
| TrifluridineViroptic® | III | 25 | NCT07525206 |
| PanitumumabVectibix, Panitumumbab | III | 22 | NCT05863195 |
| RegorafenibRegorafinib, BAY73-4506 | II–III | 21 | NCT05462613 |
| AtezolizumabTecentriq, MPDL3280A | II–III | 19 | NCT05770102 |
Sorted by most advanced phase and number of active trials. Showing 15 of 154 drugs.
All 534 drugs, with the details
In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.
Open in Phuturdex →Specific forms
- Rectal neoplasm 131 drugs
- Colonic neoplasm 157 drugs
- Anus neoplasm 28 drugs
- Pancreatic neoplasm 395 drugs
- Non-small-cell lung carcinoma 726 drugs
- Lung neoplasm 348 drugs
- Neoplasm 671 drugs
- Stomach neoplasm 340 drugs
- Uterine cervix neoplasm 224 drugs
- Breast neoplasm 593 drugs
- Thyroid neoplasm 99 drugs
- Sarcoma 204 drugs
Broader categories
- Digestive System Diseases 36 drugs
- Gastrointestinal disease 22 drugs
- Colonic disease 11 drugs
- Intestinal disease 15 drugs
- Rectal disease 9 drugs
- Digestive system neoplasm 37 drugs
Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D015179 “Colorectal Neoplasms”.