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Drugs in development · updated 30 October 2026

Nivolumab: clinical trials and development status

Other names and codes: Opdivo, ONO-4538

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 19 June 2015

As of 30 October 2026 Nivolumab is in 555 active clinical trials (recruiting or ongoing, phases I–III) for 214 diseases. The most advanced phase is III.

555Active trials
IIIMost advanced phase
214Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Nivolumab and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 214 diseases.

DiseaseMost advanced phaseActive trialsReference trial
MelanomaIII91NCT07221734
Non-small-cell lung carcinomaIII78NCT06561386
Renal cell carcinomaIII51NCT07620574
MetastasisIII30NCT07221734
Colorectal neoplasmIII29NCT07620574
Lung neoplasmIII29NCT03391869
NeoplasmIII28NCT07620574
Head and neck squamous cell carcinomaIII26NCT03576417
Stomach neoplasmIII26NCT07431281
Hepatocellular carcinomaIII24NCT07620574
Transitional cell carcinomaIII20NCT07720284
Hodgkin lymphomaIII18NCT03907488
Bladder neoplasmIII17NCT07720284
Esophageal neoplasmIII16NCT07431281
Esophagus adenocarcinomaIII16NCT07431281
Brain NeoplasmsIII15NCT05317858
Prostatic NeoplasmsIII11NCT07620574
Colonic neoplasmIII9NCT06490536
Kidney neoplasmIII9NCT06364631
Clear-cell metastatic renal cell carcinomaIII8NCT07383441
Skin neoplasmIII8NCT07815574
CarcinomaIII7NCT03937219
Lung small cell carcinomaIII7NCT06646276
MesotheliomaIII7NCT06097728
Uveal melanomaII–III7NCT06581406
Malignant mesotheliomaIII6NCT06097728
Anus neoplasmIII5NCT04444921
Esophageal squamous cell carcinomaIII5NCT06022861
Liver neoplasmIII5NCT03383458
Squamous cell carcinomaII–III5NCT03952585

Everything on Nivolumab

In Phuturdex you get every trial with sponsors, countries and dates, development events, FDA and EMA approvals, patents and exclusivities, orphan designations and safety alerts, with PDF and Excel export. Free until 31 March 2027.

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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