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Drugs in development · updated 30 October 2026

Kidney neoplasm: drugs in development

As of 30 October 2026 there are 77 active clinical trials (recruiting or ongoing, phases I–III) on 92 drugs for kidney neoplasm. 48 are experimental, that is not yet approved in the United States.

77Active trials
48Experimental drugs
3Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
CasdatifanIII5NCT07011719
ICIsIII1NCT06726421
SavolitinibAZD6094III1NCT03091192
CadonilimabAK104, CandonilimabI–II2NCT06577961
SasanlimabZumrad®I–II2NCT05665361
ZimberelimabAB122, GLS-010II2NCT07397611
177Lu-TLX250II1NCT07870746
AB-2100I–II1NCT06245915
AlintegimodI–II1NCT06362369
AnlotinibAL3818, AnrotinibII1NCT06211790
EB-701I–II1NCT07551349
EBNK-001I–II1NCT07410676
Elraglusib Oral Tablets9-ING-41II1NCT03678883
GuadecitabineI–II1NCT03308396
HTL0039732I–II1NCT05944237
IL-15I–II1NCT07410676
IvocizumabII1NCT06683846
Izalontamab brengitecanBL-B01D1, BMS-986507II1NCT06962787
MDX2001I–II1NCT06239194
NDI-101150I–II1NCT05128487
OrellanineI–II1NCT05287945
PF-08634404I–II1NCT07227415
PsilocybinPsilocybineII1NCT07072728
SintilimabSinitilimab, SindilimabII1NCT07715565
SL-28I–II1NCT07341737
VebreltinibPLB1001, APL-101II1NCT03175224
VorolanibI–II1NCT06577961
HC-7366I2NCT06234605
111In-XYIMSR-01I1NCT07062549
AUR107I1NCT05865002
BezlutifanI1NCT02293980
BMS-986506I1NCT07195682
DarlifarnibI1NCT06026410
DEG6498I1NCT07244835
DK210I1NCT05704985
KFA115I1NCT05544929
MK-3795I1NCT02293980
NEO-811I1NCT07300241
NXP900I1NCT05873686
OATD-02I1NCT05759923

Sorted by most advanced phase and number of active trials. Showing 40 of 48 drugs.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
IpilimumabYERVOY, ipililumab IVIII11NCT06364631
PembrolizumabKEYTRUDA, MK-3475III10NCT06364631
CabozantinibResniben®, Cabometyx®III9NCT07011719
NivolumabOpdivo, ONO-4538III9NCT06364631
AxitinibInlyta®, Axitinib Accord®III6NCT06726421
BelzutifanWelireg®III6NCT04195750
LenvatinibLenvatinib Mesilate Capsules, LevatinibIII6NCT06726421
EverolimusRAD001, EveroliumusIII3NCT04195750
PazopanibVotrient®III2NCT06726421
SunitinibSutent®, Sunitinib Accord®III2NCT03091192
AtorvastatinLipitor, Atorvaliq®III1NCT05796973
BupivacaineExparel, BupivacainIII1NCT06349668
LidocaineXylocaine, Bondlido®III1NCT06349668
MorphineArymo Er®, Morphabond Er®III1NCT06349668
AtezolizumabTecentriq, MPDL3280AI–II3NCT05944237

Sorted by most advanced phase and number of active trials. Showing 15 of 44 drugs.

All 92 drugs, with the details

In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.

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Specific forms

Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D007680 “Kidney Neoplasms”.

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