Phuturdex › Diseases › Triple-negative breast neoplasm
Drugs in development · updated 30 October 2026
Triple-negative breast neoplasm: drugs in development
As of 30 October 2026 there are 378 active clinical trials (recruiting or ongoing, phases I–III) on 334 drugs for triple-negative breast neoplasm. 221 are experimental, that is not yet approved in the United States.
Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.
Sign in free →Experimental drugs
Not yet approved by the US FDA for any indication.
Sorted by most advanced phase and number of active trials. Showing 40 of 221 drugs.
Approved drugs in new trials
Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| PembrolizumabKEYTRUDA, MK-3475 | III | 90 | NCT02954874 |
| CarboplatinCarboplatine, Paraplatin | II–III | 71 | NCT06910072 |
| PaclitaxelTaxol, Paxlitaxel | II–III | 55 | NCT06926868 |
| CyclophosphamideCyclophosphamid, Cytoxan | II–III | 40 | NCT02641847 |
| CapecitabineXeloda, Capectitabine Tablets | II–III | 30 | NCT06926868 |
| Nab-paclitaxelAbraxane, Nab-placlitaxel | II–III | 28 | NCT06926868 |
| Sacituzumab GovitecanTrodelvy® | III | 25 | NCT05633654 |
| DoxorubicinAdriamycin, Doxorubincin | II–III | 18 | NCT02641847 |
| GemcitabineGemcitabin, Gemzar | II–III | 17 | NCT07544056 |
| OlaparibAZD2281, Lynparza® | II–III | 17 | NCT03150576 |
| EpirubicinEllence® | II–III | 16 | NCT02641847 |
| ToripalimabJS001, Teripalimab | III | 14 | NCT07111832 |
| EribulinEribulin Mesilate injection, Eribulin Mcsilate Injection | III | 13 | NCT06279364 |
| DocetaxelTaxotere, Beizray® | II–III | 12 | NCT02641847 |
| AtezolizumabTecentriq, MPDL3280A | III | 9 | NCT03281954 |
Sorted by most advanced phase and number of active trials. Showing 15 of 113 drugs.
All 334 drugs, with the details
In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.
Open in Phuturdex →Broader categories
- Skin disease 34 drugs
- Skin and connective tissue diseases 3 drugs
- Breast disease 21 drugs
- Neoplasm 671 drugs
- Breast neoplasm 593 drugs
- Respiratory tract neoplasm 21 drugs
Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D064726 “Triple Negative Breast Neoplasms”.