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Drugs in development · updated 30 October 2026

Apatinib: clinical trials and development status

Other names and codes: Rivoceranib

NLM verified identityNot approved in the USNo EMA authorisationEstimated launch Dec 2027 – Oct 2028 (Phuturdex estimate)

As of 30 October 2026 Apatinib is in 121 active clinical trials (recruiting or ongoing, phases I–III) for 32 diseases. The most advanced phase is III.

121Active trials
IIIMost advanced phase
32Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Apatinib and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 32 diseases.

DiseaseMost advanced phaseActive trialsReference trial
Stomach neoplasmIII16NCT06346392
Hepatocellular carcinomaIII15NCT05198609
Breast neoplasmIII9NCT06889688
Ovarian neoplasmIII4NCT06188455
Triple-negative breast neoplasmIII4NCT06889688
AdenocarcinomaII–III3NCT04208347
Esophageal squamous cell carcinomaII–III3NCT07653451
MetastasisIII2NCT05854849
Nasopharyngeal CarcinomaIII2NCT06438627
Lung small cell carcinomaII4NCT07357532
Pancreatic neoplasmII4NCT07773363
Liver neoplasmII3NCT07684040
Biliary tract neoplasmII2NCT07569679
CholangiocarcinomaII2NCT06925516
SarcomaII2NCT04072042
Adenocarcinoma of the lungII1NCT02493582
Adrenal gland neoplasmII1NCT06831175
Adrenocortical carcinomaII1NCT06831175
Digestive system neoplasmII1NCT06099821
Endometrial neoplasmII1NCT06771154
Gastrointestinal stromal tumorII1NCT05905887
Gestational trophoblastic diseaseII1NCT05139095
Head and neck squamous cell carcinomaII1NCT05069857
LiposarcomaII1NCT06694324
Lung neoplasmI–II1NCT06607770
MedulloblastomaII1NCT04501718
Neuroendocrine tumorII1NCT06764368
Non-small-cell lung carcinomaII1NCT07031154
Radiation PneumonitisII1NCT06700421
Salivary gland neoplasmII1NCT06145308

Everything on Apatinib

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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