Phuturdex › Diseases › Adrenocortical carcinoma
Drugs in development · updated 30 October 2026
Adrenocortical carcinoma: drugs in development
As of 30 October 2026 there are 23 active clinical trials (recruiting or ongoing, phases I–III) on 28 drugs for adrenocortical carcinoma. 8 are experimental, that is not yet approved in the United States.
Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.
Sign in free →Experimental drugs
Not yet approved by the US FDA for any indication.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| ApatinibRivoceranib | II | 1 | NCT06831175 |
| CamrelizumabCarrelizumab, Carilizumab | II | 1 | NCT06831175 |
| IvonescimabAK112 | II | 1 | NCT07743138 |
| PDS01ADC | II | 1 | NCT05286814 |
| Triprolizumab | II | 1 | NCT06587802 |
| ADCT-701 | I | 1 | NCT06041516 |
| DS9051b | I | 1 | NCT07189403 |
| E7386 | I | 1 | NCT03833700 |
Sorted by most advanced phase and number of active trials.
Approved drugs in new trials
Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| PembrolizumabKEYTRUDA, MK-3475 | II | 5 | NCT05563467 |
| CabozantinibResniben®, Cabometyx® | II | 2 | NCT06900595 |
| Cabozantinib S-malateCabometyx®, Cometriq® | II | 2 | NCT02867592 |
| CemiplimabREGN2810, Libtayo® | II | 2 | NCT06900595 |
| CisplatinCis Platinum, Cisplatine | II | 2 | NCT03127774 |
| IpilimumabYERVOY, ipililumab IV | II | 2 | NCT03333616 |
| MitotaneLysodren® | II | 2 | NCT06831175 |
| NivolumabOpdivo, ONO-4538 | II | 2 | NCT03333616 |
| DexamethasoneDexametasone, Dextenza | II | 1 | NCT05286814 |
| DostarlimabTSR-042, Jemperli® | II | 1 | NCT06333314 |
| DoxorubicinAdriamycin, Doxorubincin | II | 1 | NCT05913427 |
| EtoposideAvopef®, Etopophos Preservative Free® | II | 1 | NCT05913427 |
| FloxuridineFUDR | II | 1 | NCT05286814 |
| LenvatinibLenvatinib Mesilate Capsules, Levatinib | II | 1 | NCT05036434 |
| Megestrol AcetateMegace Es®, Megace® | II | 1 | NCT05913427 |
Sorted by most advanced phase and number of active trials. Showing 15 of 20 drugs.
All 28 drugs, with the details
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Open in Phuturdex →Broader categories
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Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D018268 “Adrenocortical Carcinoma”. Prevalence: Orphanet.