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Drugs in development · updated 30 October 2026

Lenvatinib: clinical trials and development status

Other names and codes: Lenvima, Kisplyx

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 28 May 2015

As of 30 October 2026 Lenvatinib is in 227 active clinical trials (recruiting or ongoing, phases I–III) for 63 diseases. The most advanced phase is III.

227Active trials
IIIMost advanced phase
63Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Lenvatinib and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 63 diseases.

DiseaseMost advanced phaseActive trialsReference trial
Hepatocellular carcinomaIII51NCT05301842
Renal cell carcinomaIII24NCT04736706
CholangiocarcinomaIII12NCT07691515
NeoplasmIII10NCT07405164
Liver neoplasmIII9NCT05301842
Kidney neoplasmIII6NCT06726421
Uterine cervix neoplasmII–III6NCT07177716
MetastasisIII3NCT07537946
Clear-cell metastatic renal cell carcinomaIII2NCT07383441
Hematologic neoplasmIII1NCT03486873
Von Hippel-Lindau diseaseIII1NCT07405164
Biliary tract neoplasmII11NCT07829874
Endometrial neoplasmII8NCT04781088
Stomach neoplasmII7NCT07902648
Non-small-cell lung carcinomaII5NCT07894367
Adenoid cystic carcinomaII4NCT04209660
Breast neoplasmII4NCT05181033
Esophageal squamous cell carcinomaII4NCT07686926
MelanomaII4NCT07847359
Thyroid neoplasmII4NCT07874321
Anaplastic thyroid carcinomaII3NCT04171622
Colorectal neoplasmI–II3NCT04008797
Neuroendocrine tumorII3NCT03950609
Ovarian neoplasmII3NCT04781088
Triple-negative breast neoplasmI–II3NCT04300556
AdenocarcinomaII2NCT07368985
Head and neck squamous cell carcinomaII2NCT05433116
Lung small cell carcinomaI–II2NCT04938817
Malignant mesotheliomaII2NCT06318286
Ovarian epithelial carcinomaII2NCT04519151

Everything on Lenvatinib

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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