PhuturdexDrug Pipeline Intelligence

Phuturdex › Diseases › Non-small-cell lung carcinoma

Drugs in development · updated 30 October 2026

Non-small-cell lung carcinoma: drugs in development

As of 30 October 2026 there are 1,218 active clinical trials (recruiting or ongoing, phases I–III) on 726 drugs for non-small-cell lung carcinoma. 549 are experimental, that is not yet approved in the United States.

1,218Active trials
549Experimental drugs
92Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

Sign in free →

Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
FurmonertinibFirmonertinib, Furmonertinib Mesilate TabletsIII30NCT07185997
IvonescimabAK112III26NCT05899608
Sacituzumab TirumotecanSKB264III23NCT06305754
AnlotinibAL3818, AnrotinibII–III19NCT04322617
AdebrelimabSHR-1316, AdebelimabIII18NCT07896005
Izalontamab brengitecanBL-B01D1, BMS-986507II–III15NCT07642024
SintilimabSinitilimab, SindilimabIII15NCT05116462
AlmonertinibAumolertinib, HS-10296II–III14NCT06417008
RilvegostomigAZD2936III12NCT06692738
PumitamigII–III11NCT06712316
PLB1004III9NCT06281964
VebreltinibPLB1001, APL-101III9NCT06930794
BenmelstobartTQB2450III7NCT06955325
DivarasibGDC-6036II–III7NCT03178552
OleclumabMEDI9447III7NCT05221840
SavolitinibAZD6094III7NCT05009836
CadonilimabAK104, CandonilimabIII6NCT06617416
SYS6010III6NCT06927986
VolrustomigMEDI5752III6NCT05984277
ZimberelimabAB122, GLS-010III6NCT06431633
BudigalimabABBV-181II–III5NCT06236438
CeralasertibAZD6738III5NCT06732401
DomvanalimabAB154III5NCT05211895
OlomorasibLY3537982III5NCT06119581
QL1706III5NCT05487391
CalderasibIII4NCT07554339
HS-20093III4NCT07464327
HS-20117II–III4NCT06417008
IcotinibIII4NCT06955325
SI-B001II–III4NCT05020769
Sigvotatug vedotinIII4NCT06758401
Telisotuzumab AdizutecanII–III4NCT07155187
YL202III4NCT07416994
ZipalertinibTAS6417, CLN-081III4NCT07128199
BefotertinibIII3NCT06041776
BelrestotugIII3NCT06472076
EnlonstobartSG001II–III3NCT07662811
FianlimabREGN3767II–III3NCT05800015
HS-10370III3NCT07822542
Intismeran autogenemRNA-4157III3NCT07513376

Sorted by most advanced phase and number of active trials. Showing 40 of 549 drugs.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
CarboplatinCarboplatine, ParaplatinII–III215NCT07365319
PembrolizumabKEYTRUDA, MK-3475II–III191NCT04613596
PemetrexedAxtle®, Pemfexy®II–III182NCT07365319
CisplatinCis Platinum, CisplatineII–III124NCT07365319
OsimertinibAZD9291, TagrissoII–III93NCT07155187
PaclitaxelTaxol, PaxlitaxelII–III90NCT07365319
NivolumabOpdivo, ONO-4538II–III78NCT04929041
DocetaxelTaxotere, Beizray®II–III74NCT07718737
DurvalumabMEDI4736, Imfinzi®III58NCT04092283
Bevacizumabavastin, MVASIII–III39NCT03178552
GemcitabineGemcitabin, GemzarII–III38NCT03178552
TislelizumabTisleizumab, TiselizumabII–III38NCT07662811
Nab-paclitaxelAbraxane, Nab-placlitaxelII–III37NCT07365319
AtezolizumabTecentriq, MPDL3280AII–III34NCT03178552
CemiplimabREGN2810, Libtayo®II–III34NCT06616584

Sorted by most advanced phase and number of active trials. Showing 15 of 177 drugs.

All 726 drugs, with the details

In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.

Open in Phuturdex →

Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D002289 “Carcinoma, Non-Small-Cell Lung”.

ItalianoFrançaisDeutsch