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Drugs in development · updated 30 October 2026

Sigvotatug vedotin: clinical trials and development status

FDA substance registryNot approved in the USNo EMA authorisationEstimated launch Dec 2027 – Oct 2028 (Phuturdex estimate)

As of 30 October 2026 Sigvotatug vedotin is in 4 active clinical trials (recruiting or ongoing, phases I–III) for 12 diseases. The most advanced phase is III.

4Active trials
IIIMost advanced phase
12Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Sigvotatug vedotin and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Non-small-cell lung carcinomaIII4NCT06758401
Lung neoplasmIII2NCT06758401
CarcinomaIII1NCT06758401
Lung diseaseIII1NCT06012435
Bladder neoplasmI1NCT04389632
Esophageal neoplasmI1NCT04389632
Esophageal squamous cell carcinomaI1NCT04389632
Esophagus adenocarcinomaI1NCT04389632
Head and neck squamous cell carcinomaI1NCT04389632
Ovarian neoplasmI1NCT04389632
Stomach neoplasmI1NCT04389632
Uterine cervix neoplasmI1NCT04389632

Everything on Sigvotatug vedotin

In Phuturdex you get every trial with sponsors, countries and dates, development events, FDA and EMA approvals, patents and exclusivities, orphan designations and safety alerts, with PDF and Excel export. Free until 31 March 2027.

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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