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Drugs in development · updated 30 October 2026

Lung neoplasm: drugs in development

As of 30 October 2026 there are 421 active clinical trials (recruiting or ongoing, phases I–III) on 348 drugs for lung neoplasm. 208 are experimental, that is not yet approved in the United States.

421Active trials
208Experimental drugs
27Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
PLB1004III7NCT06281964
Sacituzumab TirumotecanSKB264III5NCT06312137
VebreltinibPLB1001, APL-101III5NCT06970782
FurmonertinibFirmonertinib, Furmonertinib Mesilate TabletsIII4NCT07185997
AlmonertinibAumolertinib, HS-10296III3NCT04841811
CeralasertibAZD6738III3NCT06732401
OpnurasibJDQ443III3NCT05132075
PF-08634404III3NCT07222566
PumitamigII–III3NCT06712316
DivarasibGDC-6036III2NCT06793215
FianlimabREGN3767II–III2NCT05800015
JYP0322III2NCT07154368
Sigvotatug vedotinIII2NCT06758401
ZipalertinibTAS6417, CLN-081III2NCT07128199
AbenacianineIII1NCT07499674
AcasunlimabIII1NCT06635824
Anamorelin HydrochlorideAdlumiz®II–III1NCT03637816
BL-M14D1III1NCT07625644
BMS-986504II–III1NCT07063745
HD204III1NCT03390686
NeladalkibIII1NCT06765109
OlomorasibLY3537982III1NCT06119581
QL1706III1NCT05690945
QL2107III1NCT07162883
TilesizumabIII1NCT05690945
Toluenesulfonamide InjectionIII1NCT06607796
ZoldonrasibIII1NCT07777822
IvonescimabAK112I–II4NCT07602855
RMC-6236I–II4NCT06922591
SintilimabSinitilimab, SindilimabII4NCT07745790
AdebrelimabSHR-1316, AdebelimabII3NCT07890636
BerzosertibI–II3NCT04216316
ElironrasibRMC-6291I–II3NCT06162221
RMC-9805I–II3NCT06922591
[68Ga]CBP8II2NCT04485286
AnlotinibAL3818, AnrotinibII2NCT07307443
CVL237II2NCT07446049
EnvafolimabKN035II2NCT07818304
OleclumabMEDI9447II2NCT05061550
SapanisertibII2NCT02465060

Sorted by most advanced phase and number of active trials. Showing 40 of 208 drugs.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
PembrolizumabKEYTRUDA, MK-3475II–III76NCT07063745
CarboplatinCarboplatine, ParaplatinII–III72NCT07063745
PemetrexedAxtle®, Pemfexy®II–III54NCT07063745
CisplatinCis Platinum, CisplatineII–III40NCT07063745
DurvalumabMEDI4736, Imfinzi®III39NCT04092283
OsimertinibAZD9291, TagrissoIII31NCT04181060
PaclitaxelTaxol, PaxlitaxelII–III31NCT07063745
AtezolizumabTecentriq, MPDL3280AIII29NCT04214262
NivolumabOpdivo, ONO-4538II–III29NCT04929041
GemcitabineGemcitabin, GemzarII–III23NCT05096663
EtoposideAvopef®, Etopophos Preservative Free®III20NCT04092283
DocetaxelTaxotere, Beizray®II–III18NCT06616584
Bevacizumabavastin, MVASIIII17NCT04181060
Nab-paclitaxelAbraxane, Nab-placlitaxelII–III15NCT07063745
IpilimumabYERVOY, ipililumab IVII–III13NCT04929041

Sorted by most advanced phase and number of active trials. Showing 15 of 140 drugs.

All 348 drugs, with the details

In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.

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Specific forms

Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D008175 “Lung Neoplasms”.

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