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Drugs in development · updated 30 October 2026

Osimertinib: clinical trials and development status

Other names and codes: AZD9291, Tagrisso

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 1 February 2016

As of 30 October 2026 Osimertinib is in 140 active clinical trials (recruiting or ongoing, phases I–III) for 36 diseases. The most advanced phase is III.

140Active trials
IIIMost advanced phase
36Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Osimertinib and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 36 diseases.

DiseaseMost advanced phaseActive trialsReference trial
Non-small-cell lung carcinomaIII93NCT07680790
Lung neoplasmIII31NCT04181060
NeoplasmIII6NCT05629234
CarcinomaIII5NCT06417814
MetastasisIII5NCT04035486
Residual neoplasmIII1NCT06323148
Brain NeoplasmsII5NCT05948813
Breast neoplasmII3NCT02465060
Colorectal neoplasmII2NCT02465060
Hematologic neoplasmII2NCT02465060
LymphomaII2NCT02465060
Multiple myelomaII2NCT02465060
Adenocarcinoma of the lungII1NCT05528458
Bladder neoplasmII1NCT02465060
Colonic neoplasmII1NCT02465060
Endometrial neoplasmII1NCT02465060
Esophageal neoplasmII1NCT02465060
GliomaII1NCT02465060
Head and neck squamous cell carcinomaI–II1NCT05785741
Hepatocellular carcinomaII1NCT02465060
Lung small cell carcinomaI–II1NCT07153055
MelanomaII1NCT02465060
MesotheliomaI–II1NCT04665206
Ovarian neoplasmII1NCT02465060
Pancreatic neoplasmII1NCT02465060
Prostatic NeoplasmsII1NCT02465060
Rectal neoplasmII1NCT02465060
Squamous cell carcinomaII1NCT06383728
Stomach neoplasmII1NCT02465060
Thyroid neoplasmII1NCT02465060

Everything on Osimertinib

In Phuturdex you get every trial with sponsors, countries and dates, development events, FDA and EMA approvals, patents and exclusivities, orphan designations and safety alerts, with PDF and Excel export. Free until 31 March 2027.

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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