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Drugs in development · updated 30 October 2026

Prostatic Neoplasms: drugs in development

As of 30 October 2026 there are 522 active clinical trials (recruiting or ongoing, phases I–III) on 383 drugs for prostatic Neoplasms. 230 are experimental, that is not yet approved in the United States.

522Active trials
230Experimental drugs
23Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
AntiandrogenIII7NCT06205316
XaluritamigIII7NCT07213674
SaruparibAZD5305III6NCT07711002
RezvilutamideIII5NCT05983783
JNJ-101556143III3NCT07906717
MevrometostatPF-06821497III3NCT06551324
18F-PSMA-1007III2NCT05520255
AAA817II–III2NCT06780670
CurcuminIII2NCT03769766
Ifinatamab DeruxtecanIII2NCT06925737
Ra223III2NCT02194842
177Lu-NYM032III1NCT07795268
177Lu-TLX591III1NCT06520345
[68Ga]-LNTH-2401II–III1NCT07831824
BMS-986365III1NCT06764485
BuserelinIII1NCT04513717
INR101III1NCT06922903
OpevesostatODM-208III1NCT06136650
PredinsoneIII1NCT06764485
QLC5508III1NCT07632690
RinzimetostatIII1NCT07723248
SatraplatinOrplatna®II–III1NCT03258320
ZanzalintinibXL092III1NCT07620574
AZD2287I–II3NCT07590934
NezastomigREGN5678I–II3NCT07850921
PalacaparibAZD9574I–II3NCT07181161
PDS01ADCI–II3NCT04633252
225Ac-J591I–II2NCT04946370
225Ac-LNC1011I–II2NCT07363486
AdavosertibAZD1775II2NCT02465060
ASP5541II2NCT07005154
BalstilimabBalstililmab, BalstilmabI–II2NCT06782555
DCFPyLpiflufolastatII2NCT04700332
EnoblituzumabII2NCT02923180
HomoharringtonineOmacetaxineII2NCT07163910
HRS-1167I–II2NCT06568094
HRS-5041I–II2NCT06568094
HS-20093II2NCT07230106
IpatasertibII2NCT02465060
JSB462II2NCT07047118

Sorted by most advanced phase and number of active trials. Showing 40 of 230 drugs.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
AbirateroneZytiga, Yonsa®II–III78NCT04787744
EnzalutamideDeutenzalutamide, XtandiII–III70NCT04787744
PrednisonePredinisone, CortancylII–III52NCT04787744
ApalutamideJNJ 56021927, Erleada®II–III44NCT04787744
DocetaxelTaxotere, Beizray®II–III44NCT04787744
DarolutamideNubeqa, ODM-201II–III42NCT07852195
Leuprolide AcetateLeuprorelin, LupronII–III31NCT04787744
Pluvicto177Lu-PSMA-617, Lutetium Lu 177 Vipivotide TetraxetanII–III27NCT07852195
DegarelixFirmagon, Degarelix Accord®II–III20NCT04787744
CarboplatinCarboplatine, ParaplatinIII17NCT06439225
RelugolixOrgovyx®II–III16NCT04787744
BicalutamideCasodex®II–III15NCT04787744
GoserelinZOLADEXII–III15NCT04787744
CabazitaxelJevtana Kit®, Jevtana®II–III14NCT07852195
TriptorelinTriptorelin Embonate, Triprorelin AcetateII–III14NCT04787744

Sorted by most advanced phase and number of active trials. Showing 15 of 153 drugs.

All 383 drugs, with the details

In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.

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Specific forms

Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: NLM MeSH; NLM MeSH term: D011471 “Prostatic Neoplasms”.

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