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Drugs in development · updated 30 October 2026

Enzalutamide: clinical trials and development status

Other names and codes: Xtandi, HC-1119

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 21 June 2013

As of 30 October 2026 Enzalutamide is in 117 active clinical trials (recruiting or ongoing, phases I–III) for 37 diseases. The most advanced phase is III.

117Active trials
IIIMost advanced phase
37Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Enzalutamide and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 37 diseases.

DiseaseMost advanced phaseActive trialsReference trial
Prostatic NeoplasmsIII70NCT06551324
NeoplasmIII7NCT07620574
MetastasisIII6NCT07751133
AdenocarcinomaIII5NCT06592924
Hepatocellular carcinomaIII3NCT07620574
Colorectal neoplasmIII2NCT07620574
Renal cell carcinomaIII1NCT07620574
Castration-resistant prostatic neoplasmII6NCT07717268
Breast neoplasmII3NCT02955394
Endometrial neoplasmI–II2NCT04104776
Lung small cell carcinomaI–II2NCT05914116
MelanomaI–II2NCT05914116
Non-small-cell lung carcinomaI–II2NCT05914116
Triple-negative breast neoplasmII2NCT02750358
Uterine cervix neoplasmI–II2NCT05914116
B-cell lymphomaI–II1NCT04104776
Bladder neoplasmI–II1NCT05057013
Diffuse large B-cell lymphomaI–II1NCT04104776
Esophageal neoplasmI–II1NCT05057013
Esophageal squamous cell carcinomaI–II1NCT05914116
Head and neck squamous cell carcinomaI–II1NCT05914116
Immune System DiseasesI–II1NCT04104776
Immunoproliferative disorderI–II1NCT04104776
Lymphatic system diseaseI–II1NCT04104776
LymphomaI–II1NCT04104776
Lymphoproliferative disordersI–II1NCT04104776
Malignant mesotheliomaI–II1NCT04104776
Non-Hodgkin lymphomaI–II1NCT04104776
Ovarian neoplasmI–II1NCT05057013
Pancreatic neoplasmI–II1NCT05057013

Everything on Enzalutamide

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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