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Drugs in development · updated 30 October 2026

B-cell lymphoma: drugs in development

As of 30 October 2026 there are 179 active clinical trials (recruiting or ongoing, phases I–III) on 152 drugs for b-cell lymphoma. 88 are experimental, that is not yet approved in the United States.

179Active trials
88Experimental drugs
2Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
OdronextamabOrdspono®II–III3NCT05991388
NX-5948III2NCT07516093
CD19I–II7NCT05442515
RN1701I–II3NCT07506668
SurovatamigAZD0486I–II3NCT06564038
CD22I–II2NCT05091541
JS203II2NCT07081022
SsCART-19I–II2NCT06987916
4SCAR19I–II1NCT04429438
4SCAR20I–II1NCT04429438
ALETA-001I–II1NCT06045910
AT101I–II1NCT05338931
AutoleucelII1NCT07077512
AVM0703I–II1NCT04329728
AZD4512I–II1NCT07123454
CD19-CD34tI–II1NCT05702853
ChidamideTucidinostat, HBI-8000II1NCT06158386
CLLS52I–II1NCT05607420
CTX112I–II1NCT05643742
CUCART19II1NCT06462248
DS3790aI–II1NCT07220616
EB103I–II1NCT06343311
HP-002I–II1NCT07658352
JCAR017II1NCT04245839
JNJ-90014496I–II1NCT05421663
LinperlisibII1NCT06158386
MaplirpaceptII1NCT05507541
NemtabrutinibI–II1NCT03162536
OntorpaceptII1NCT05507541
Relmacabtagene autoleucelRelma-celII1NCT06365671
Sepantronium BromideII1NCT05263583
SintilimabSinitilimab, SindilimabII1NCT07077512
STP938I–II1NCT05463263
SYS6055I–II1NCT07905261
TacabrutidegI–II1NCT06634589
TAK-007II1NCT05020015
TQB3702II1NCT06566586
TulmimetostatCPI-0209I–II1NCT04104776
UB-VV400I–II1NCT07735533
UCART20x22I–II1NCT05607420

Sorted by most advanced phase and number of active trials. Showing 40 of 88 drugs.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
CyclophosphamideCyclophosphamid, CytoxanIII41NCT04529772
RituximabRuxience, RituxanII–III30NCT05991388
DoxorubicinAdriamycin, DoxorubincinIII14NCT04529772
PrednisonePredinisone, CortancylIII13NCT04529772
VincristineVincristin, Oncovin [vincristine]III13NCT04529772
EtoposideAvopef®, Etopophos Preservative Free®II–III10NCT05991388
BendamustineBendamustin, BedamustineIII9NCT05023980
DexamethasoneDexametasone, DextenzaII–III8NCT05991388
PirtobrutinibJaypirca®III8NCT05023980
VenetoclaxVentoclax, Venclexta®III6NCT04965493
ZanubrutinibBGB-3111, Brukinsa®III6NCT06742996
AcalabrutinibACP-196, Calquence®III5NCT04529772
GemcitabineGemcitabin, GemzarIII5NCT06230224
CarboplatinCarboplatine, ParaplatinII–III4NCT05991388
IfosfamideII–III4NCT05991388

Sorted by most advanced phase and number of active trials. Showing 15 of 64 drugs.

All 152 drugs, with the details

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Specific forms

Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D016393 “Lymphoma, B-Cell”.

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