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Drugs in development · updated 30 October 2026

Pirtobrutinib: clinical trials and development status

Other names and codes: Jaypirca

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 30 October 2023

As of 30 October 2026 Pirtobrutinib is in 52 active clinical trials (recruiting or ongoing, phases I–III) for 17 diseases. The most advanced phase is III.

52Active trials
IIIMost advanced phase
17Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Pirtobrutinib and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Chronic lymphocytic leukemiaIII20NCT06973187
Mantle cell lymphomaIII12NCT04662255
Non-Hodgkin lymphomaIII9NCT05023980
B-cell lymphomaIII8NCT05023980
Hematologic DiseasesIII5NCT05023980
B-cell leukemiaIII4NCT05254743
LymphomaIII4NCT04662255
Lymphoid leukemiaIII1NCT05254743
Interdigitating dendritic cell sarcomaII5NCT07812493
LeukemiaII3NCT06812715
Waldenstrom MacroglobulinemiaII3NCT07231952
Follicular lymphomaII2NCT06948786
Lymphoma, B-Cell, Marginal ZoneII2NCT06390956
Autoimmune thrombocytopenic purpuraI–II1NCT06721013
Hematologic neoplasmII1NCT05529069
Burkitt lymphomaI2NCT03666000
Diffuse large B-cell lymphomaI1NCT05990465

Everything on Pirtobrutinib

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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