Phuturdex › Diseases › Lymphatic system disease
Drugs in development · updated 30 October 2026
Lymphatic system disease: drugs in development
As of 30 October 2026 there are 9 active clinical trials (recruiting or ongoing, phases I–III) on 20 drugs for lymphatic system disease. 5 are experimental, that is not yet approved in the United States.
Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.
Sign in free →Experimental drugs
Not yet approved by the US FDA for any indication.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| EmavusertibCA-4948 | I–II | 1 | NCT03328078 |
| Nemtabrutinib | I–II | 1 | NCT03162536 |
| Sepantronium Bromide | II | 1 | NCT05263583 |
| TulmimetostatCPI-0209 | I–II | 1 | NCT04104776 |
| RimiducidAP1903 | I | 1 | NCT03696784 |
Sorted by most advanced phase and number of active trials.
Approved drugs in new trials
Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.
| Drug | Most advanced phase | Active trials | Reference trial |
|---|---|---|---|
| CyclophosphamideCyclophosphamid, Cytoxan | III | 4 | NCT04529772 |
| AcalabrutinibACP-196, Calquence® | III | 1 | NCT04529772 |
| DoxorubicinAdriamycin, Doxorubincin | III | 1 | NCT04529772 |
| PrednisonePredinisone, Cortancyl | III | 1 | NCT04529772 |
| RituximabRuxience, Rituxan | III | 1 | NCT04529772 |
| VincristineVincristin, Oncovin [vincristine] | III | 1 | NCT04529772 |
| FludarabineFludara, FLUDARABIN | II | 4 | NCT06001385 |
| BusulfanBusulphan, Busulfex® | II | 2 | NCT06001385 |
| MelphalanEvomela®, Hepzato® | II | 2 | NCT06001385 |
| MesnaUromitexan, Mesnex® | II | 2 | NCT06001385 |
| Mycophenolate MofetilMycophenolate, Cellcept | II | 2 | NCT06001385 |
| TacrolimusEnvarsus XR, Prograf® | II | 2 | NCT06001385 |
| EnzalutamideDeutenzalutamide, Xtandi | I–II | 1 | NCT04104776 |
| IbrutinibPCI 32765, Imbruvica® | I–II | 1 | NCT03328078 |
| BendamustineBendamustin, Bedamustine | I | 2 | NCT03696784 |
Sorted by most advanced phase and number of active trials.
All 20 drugs, with the details
In Phuturdex every drug has all its trials, sponsors and countries, FDA and EMA approvals, orphan designations and safety alerts. Free until 31 March 2027.
Open in Phuturdex →Specific forms
- Diffuse large B-cell lymphoma 177 drugs
- Non-Hodgkin lymphoma 269 drugs
- Lymphoma 252 drugs
- Chronic lymphocytic leukemia 137 drugs
- Precursor lymphoblastic lymphoma/leukemia 163 drugs
- Follicular lymphoma 144 drugs
- B-cell lymphoma 152 drugs
- Mantle cell lymphoma 108 drugs
- Burkitt lymphoma 113 drugs
- Lymphoma, B-Cell, Marginal Zone 86 drugs
- Acute myeloid leukemia 314 drugs
- Hodgkin lymphoma 93 drugs
Broader categories
- Neoplasm 671 drugs
- Hematologic Diseases 57 drugs
- Immune System Diseases 54 drugs
- Non-Hodgkin lymphoma 269 drugs
- Lymphoproliferative disorders 51 drugs
- Immunoproliferative disorder 16 drugs
Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D008206 “Lymphatic Diseases”.