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Drugs in development · updated 30 October 2026

Melphalan: clinical trials and development status

Other names and codes: Evomela, Hepzato, Alkeran, Phelinun

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 16 November 2020

As of 30 October 2026 Melphalan is in 104 active clinical trials (recruiting or ongoing, phases I–III) for 133 diseases. The most advanced phase is III.

104Active trials
IIIMost advanced phase
133Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Melphalan and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 133 diseases.

DiseaseMost advanced phaseActive trialsReference trial
Acute myeloid leukemiaIII29NCT05457556
Myelodysplastic SyndromesIII24NCT05457556
Multiple myelomaIII20NCT07903506
Precursor lymphoblastic lymphoma/leukemiaIII19NCT05457556
LeukemiaIII5NCT05477589
NeuroblastomaIII5NCT06172296
Acute biphenotypic leukaemiaIII4NCT05457556
RetinoblastomaIII4NCT04799002
NeoplasmIII3NCT05477589
GanglioneuroblastomaIII2NCT06172296
Smoldering Multiple MyelomaIII2NCT00114101
Immunoglobulin Light-chain AmyloidosisIII1NCT06022939
Non-Hodgkin lymphomaII10NCT03849651
Hodgkin lymphomaII9NCT03849651
Hematologic neoplasmII8NCT05735717
Leukemia, Myelogenous, Chronic, BCR-ABL PositiveII8NCT03849651
Myeloproliferative disordersII7NCT05564390
Chronic myelomonocytic leukemiaII6NCT01885689
Graft-versus-host diseaseII6NCT06815003
MyelofibrosisII6NCT07228624
Aplastic anemiaII5NCT00544115
Mantle cell lymphomaII5NCT00544115
Chronic lymphocytic leukemiaII4NCT06001385
Juvenile myelomonocytic leukemiaII4NCT03849651
LymphomaII4NCT06001385
Uveal melanomaII4NCT07276386
B-cell leukemiaII3NCT06001385
Burkitt lymphomaII3NCT00544115
Crohn's diseaseII3NCT01962415
Diffuse large B-cell lymphomaII3NCT02570542

Everything on Melphalan

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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