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Drugs in development · updated 30 October 2026

Chidamide: clinical trials and development status

Other names and codes: Tucidinostat, HBI-8000

NLM verified identityNot approved in the USNo EMA authorisationEstimated launch Dec 2027 – Oct 2028 (Phuturdex estimate)

As of 30 October 2026 Chidamide is in 87 active clinical trials (recruiting or ongoing, phases I–III) for 32 diseases. The most advanced phase is III.

87Active trials
IIIMost advanced phase
32Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Chidamide and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 32 diseases.

DiseaseMost advanced phaseActive trialsReference trial
Peripheral T-cell lymphomaIII16NCT06947967
Acute myeloid leukemiaIII10NCT07514936
Diffuse large B-cell lymphomaIII8NCT07493109
Colorectal neoplasmIII2NCT06497985
Precursor T-cell lymphoblastic leukemiaIII2NCT07774377
Brain NeoplasmsIII1NCT04674683
MelanomaIII1NCT04674683
Acquired Immunodeficiency SyndromeI–II2NCT07577986
Colonic neoplasmII2NCT06709885
Pancreatic neoplasmII2NCT06951997
T-cell lymphomaII2NCT06151106
Acute monocytic leukemiaII1NCT05566054
B-cell lymphomaII1NCT06158386
Breast neoplasmII1NCT06547476
CholangiocarcinomaII1NCT07570849
Cutaneous T cell lymphomaI–II1NCT07754890
Epstein–Barr virus infectionI–II1NCT07133776
Follicular lymphomaII1NCT06158386
InfectionI–II1NCT07133776
Interdigitating dendritic cell sarcomaII1NCT06891157
Multiple myelomaI–II1NCT04025450
Myelodysplastic SyndromesII1NCT07616336
Nasopharyngeal CarcinomaI–II1NCT07320963
NeuroblastomaII1NCT07318831
Non-Hodgkin lymphomaII1NCT06158386
Non-small-cell lung carcinomaII1NCT07412262
OsteosarcomaII1NCT06637007
Pancreatic cancer, adultII1NCT06584227
Philadelphia chromosomeII1NCT06220487
Precursor lymphoblastic lymphoma/leukemiaII1NCT06220487

Everything on Chidamide

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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