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Drugs in development · updated 30 October 2026

Philadelphia chromosome: drugs in development

As of 30 October 2026 there are 5 active clinical trials (recruiting or ongoing, phases I–III) on 13 drugs for philadelphia chromosome. 4 are experimental, that is not yet approved in the United States.

5Active trials
4Experimental drugs
1Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
ELVN-001III1NCT07905183
CD19I–II1NCT05442515
ChidamideTucidinostat, HBI-8000II1NCT06220487
OlverembatinibHQP1351II1NCT06220487

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
AsciminibABL001, Scemblix®III2NCT04971226
NilotinibDanziten®, Cavhanza®III2NCT04971226
BosutinibBosulif®III1NCT04971226
DasatinibPhyrago®, Sprycel®III1NCT04971226
ImatinibSTI571, Imkeldi®III1NCT04971226
BlinatumomabBlincyto®II1NCT06220487
CyclophosphamideCyclophosphamid, CytoxanI–II1NCT05442515
FludarabineFludara, FLUDARABINI–II1NCT05442515
PrednisonePredinisone, CortancylII1NCT06220487

Sorted by most advanced phase and number of active trials.

All 13 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D010677 “Philadelphia Chromosome”.

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