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Drugs in development · updated 30 October 2026

Cutaneous T cell lymphoma: drugs in development

Rare diseasePrevalence 1-5 / 10 000 according to Orphanet · ORPHA:171901

As of 30 October 2026 there are 38 active clinical trials (recruiting or ongoing, phases I–III) on 46 drugs for cutaneous T cell lymphoma. 15 are experimental, that is not yet approved in the United States.

38Active trials
15Experimental drugs
0Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
GolidocitinibI–II2NCT07754890
AclarubicinI–II1NCT07535710
ChidamideTucidinostat, HBI-8000I–II1NCT07754890
MDSY-1240I–II1NCT07899632
PTX-100II1NCT06854653
ZeprumetostatII1NCT07854639
BITR2101I1NCT06385522
CHT101I1NCT06914037
DS-3201bI1NCT02732275
FenretinideI1NCT04234048
INCA036873I1NCT07195916
KK2223I1NCT07192471
Sodium-Iodide SymporterI1NCT03017820
TLN-254I1NCT06733441
DT-7012Early I1NCT07213882

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
Brentuximab VedotinSGN-35, Adcetris®III3NCT07178457
MogamulizumabPoteligeo®II5NCT04930653
CyclophosphamideCyclophosphamid, CytoxanI–II4NCT07535710
PembrolizumabKEYTRUDA, MK-3475II4NCT05313243
FludarabineFludara, FLUDARABINII3NCT00544115
RuxolitinibJakavi, Jakafi Xr®II3NCT07356245
NivolumabOpdivo, ONO-4538II2NCT02978625
BusulfanBusulphan, Busulfex®II1NCT00544115
CyclosporineCyclosporine A, Cyclosporin CapsulesII1NCT00544115
DelgocitinibAnzupgo®II1NCT07781449
DurvalumabMEDI4736, Imfinzi®I–II1NCT03011814
EtoposideAvopef®, Etopophos Preservative Free®II1NCT00544115
LenalidomideRevlimid, lenalinomideI–II1NCT03011814
MelphalanEvomela®, Hepzato®II1NCT00544115
MethotrexateJylamvo®, Reditrex®II1NCT00544115

Sorted by most advanced phase and number of active trials. Showing 15 of 31 drugs.

All 46 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D016410 “Lymphoma, T-Cell, Cutaneous”. Prevalence: Orphanet.

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