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Drugs in development · updated 30 October 2026

Ruxolitinib: clinical trials and development status

Other names and codes: Jakavi, Jakafi Xr, Opzelura

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 23 August 2012

As of 30 October 2026 Ruxolitinib is in 138 active clinical trials (recruiting or ongoing, phases I–III) for 78 diseases. The most advanced phase is III.

138Active trials
IIIMost advanced phase
78Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Ruxolitinib and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 78 diseases.

DiseaseMost advanced phaseActive trialsReference trial
MyelofibrosisIII31NCT07357727
Acute myeloid leukemiaII–III13NCT07366801
Myeloproliferative disordersIII13NCT04562389
Graft-versus-host diseaseIII9NCT06615050
Thrombocythemia, EssentialIII9NCT06079879
Polycythemia veraIII8NCT04116502
Precursor lymphoblastic lymphoma/leukemiaII–III8NCT03117751
LeukemiaII–III7NCT03117751
NeoplasmIII5NCT04468984
Bronchiolitis obliterans syndromeIII4NCT06615050
LymphomaII–III4NCT03117751
Hidradenitis suppurativaIII3NCT06959225
Skin diseaseIII3NCT06959225
VitiligoIII3NCT07595939
Atopic dermatitisIII1NCT06832618
Myelodysplastic SyndromesII9NCT06128070
Chronic myelomonocytic leukemiaII5NCT07249346
T-cell lymphomaII5NCT07356245
Aplastic anemiaII4NCT06752694
Leukemia, Myelogenous, Chronic, BCR-ABL PositiveII4NCT03610971
Cutaneous T cell lymphomaII3NCT07356245
Hemophagocytic lymphohistiocytosisII3NCT06160791
Non-Hodgkin lymphomaII3NCT04509700
Peripheral T-cell lymphomaII3NCT07356245
T-cell prolymphocytic leukemiaII3NCT07356245
Breast neoplasmII2NCT02955940
Chronic phase chronic myelogenous leukemiaII2NCT03610971
Colorectal neoplasmII2NCT02955940
Hematologic neoplasmII2NCT07359859
Hypereosinophilic syndromeII2NCT03801434

Everything on Ruxolitinib

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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