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Drugs in development · updated 30 October 2026

Hidradenitis suppurativa: drugs in development

As of 30 October 2026 there are 44 active clinical trials (recruiting or ongoing, phases I–III) on 36 drugs for hidradenitis suppurativa. 25 are experimental, that is not yet approved in the United States.

44Active trials
25Experimental drugs
5Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
LutikizumabIII3NCT06468228
PovorcitinibPovofortay®III3NCT06855498
SonelokimabIII2NCT07007637
BFB759II–III1NCT07287644
LymecyclinIII1NCT05821478
BrivekimigII1NCT07170917
CIT-013II1NCT06993233
HB0043I–II1NCT06895499
LAD191II1NCT07151937
LAD328II1NCT07547813
LT-002-158I–II1NCT06932003
NAV-240II1NCT07384975
OlatorepatideII1NCT07830329
ORKA-002II1NCT07783542
SAR445399II1NCT07225569
SCT650CII1NCT07244510
SPY072II1NCT07766005
TibulizumabII1NCT06993610
TulisokibartII1NCT06956235
ZasocitinibTAK-279II1NCT07244263
QLS12010I1NCT06946641
SBT777101I1NCT06361836
SoquelitinibCPI-818I1NCT07828860
EVO101Early I1NCT06645821
SiplizumabEarly I1NCT06326476

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
RemibrutinibLOU064, Rhapsido®III4NCT06840392
BimekizumabBimzelx®III3NCT06921850
RuxolitinibJakavi, Jakafi Xr®III3NCT06959225
UpadacitinibRinvoq Lq®, Rinvoq®III2NCT05889182
CeftriaxoneROCEPHIN, Ceftriaxone And Dextrose In Duplex Container®III1NCT05821478
MetronidazoleLikmez Oral Suspension, Nuvessa®III1NCT05821478
MoxifloxacinIZILOX, Moxeza®III1NCT05821478
RifampicinRifampin, RIFADINIII1NCT05821478
RoflumilastZoryve®, Daliresp®II2NCT07689188
AdalimumabHadlima, Simlandi®II1NCT07151937
RitlecitinibLITFULOII1NCT07228390

Sorted by most advanced phase and number of active trials.

All 36 drugs, with the details

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Broader categories

Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D017497 “Hidradenitis Suppurativa”.

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