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Drugs in development · updated 30 October 2026

Epstein–Barr virus infection: drugs in development

As of 30 October 2026 there are 20 active clinical trials (recruiting or ongoing, phases I–III) on 30 drugs for epstein–Barr virus infection. 13 are experimental, that is not yet approved in the United States.

20Active trials
13Experimental drugs
2Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
TabelecleucelEbvallo®III2NCT03394365
MEDA regimenIII1NCT07678229
MRNA-1189I–II3NCT05164094
VK-2019II2NCT04925544
ChidamideTucidinostat, HBI-8000I–II1NCT07133776
STAR0602I–II1NCT05592626
ZuberitamabII1NCT07261215
EBV gHI1NCT06908096
MRNA-1195I1NCT05831111
MRNA-1195.1I1NCT05831111
MRNA-1195.2I1NCT05831111
RimiducidAP1903I1NCT01494103
VXCO-102I1NCT07557602

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
CisplatinCis Platinum, CisplatineII–III2NCT02135042
GemcitabineGemcitabin, GemzarII–III2NCT02135042
Fluorouracil5-Fluorouracil, AdrucilII–III1NCT02135042
MethotrexateJylamvo®, Reditrex®III1NCT07678229
PaclitaxelTaxol, PaxlitaxelII–III1NCT02135042
Bevacizumabavastin, MVASII–II1NCT03813394
NivolumabOpdivo, ONO-4538II1NCT03258567
PembrolizumabKEYTRUDA, MK-3475I–II1NCT03813394
Tenofovir Disoproxil FumarateTenofovir, Viread®I–II1NCT07133776
ValganciclovirValganiclovir, Valcyte®II1NCT07138989
RituximabRuxience, RituxanI2NCT07614282
CyclophosphamideCyclophosphamid, CytoxanI1NCT05389423
DoxorubicinAdriamycin, DoxorubincinI1NCT05389423
EtoposideAvopef®, Etopophos Preservative Free®I1NCT05389423
PomalidomideImnovid, Pomalyst®I1NCT05389423

Sorted by most advanced phase and number of active trials. Showing 15 of 17 drugs.

All 30 drugs, with the details

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Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D020031 “Epstein-Barr Virus Infections”.

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