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Drugs in development · updated 30 October 2026

Sintilimab: clinical trials and development status

Other names and codes: IBI308

NLM verified identityNot approved in the USNo EMA authorisationEstimated launch Dec 2027 – Oct 2028 (Phuturdex estimate)

As of 30 October 2026 Sintilimab is in 242 active clinical trials (recruiting or ongoing, phases I–III) for 48 diseases. The most advanced phase is III.

242Active trials
IIIMost advanced phase
48Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Sintilimab and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 48 diseases.

DiseaseMost advanced phaseActive trialsReference trial
Stomach neoplasmIII29NCT05593458
Hepatocellular carcinomaIII25NCT07813572
Non-small-cell lung carcinomaIII15NCT05116462
Colorectal neoplasmIII13NCT06497985
Esophageal squamous cell carcinomaIII11NCT05357846
Rectal neoplasmII–III10NCT05484024
Head and neck squamous cell carcinomaIII6NCT07827872
Nasopharyngeal CarcinomaIII6NCT07459296
Esophageal neoplasmIII5NCT05357846
MetastasisIII5NCT07537946
Endometrial neoplasmIII2NCT06584032
Anus neoplasmIII1NCT07692152
Mouth NeoplasmsIII1NCT07827872
Pancreatic neoplasmII7NCT06050317
Biliary tract neoplasmII5NCT07831993
Colonic neoplasmII4NCT07840677
Lung neoplasmII4NCT07745790
AdenocarcinomaII2NCT06241469
Diffuse large B-cell lymphomaII2NCT07077512
GlioblastomaII2NCT07670026
Triple-negative breast neoplasmII2NCT07394387
Acquired Immunodeficiency SyndromeI–II1NCT07579247
Appendiceal neoplasmII1NCT05472948
AscitesI–II1NCT06759064
B-cell lymphomaII1NCT07077512
Breast neoplasmI–II1NCT06140576
CholangiocarcinomaII1NCT05010681
Chronic hepatitis BII1NCT07852091
Extranodal NK/T-cell lymphoma, nasal typeII1NCT07768943
Follicular lymphomaII1NCT07077512

Everything on Sintilimab

In Phuturdex you get every trial with sponsors, countries and dates, development events, FDA and EMA approvals, patents and exclusivities, orphan designations and safety alerts, with PDF and Excel export. Free until 31 March 2027.

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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