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Drugs in development · updated 30 October 2026

Sapanisertib: clinical trials and development status

NLM verified identityNot approved in the USNo EMA authorisation

As of 30 October 2026 Sapanisertib is in 10 active clinical trials (recruiting or ongoing, phases I–III) for 29 diseases. The most advanced phase is II.

10Active trials
IIMost advanced phase
29Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Sapanisertib and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
LymphomaII3NCT02465060
Multiple myelomaII3NCT02465060
Bladder neoplasmII2NCT02465060
Breast neoplasmII2NCT02465060
Endometrial neoplasmII2NCT02465060
Hepatocellular carcinomaII2NCT02465060
Lung neoplasmII2NCT02465060
Ovarian neoplasmII2NCT02465060
Carcinoma, EndometrioidII1NCT06463028
Colonic neoplasmII1NCT02465060
Colorectal neoplasmII1NCT02465060
Esophageal neoplasmII1NCT02465060
Genital DiseasesII1NCT06463028
GliomaII1NCT02465060
Hematologic neoplasmII1NCT02465060
MelanomaII1NCT02465060
Pancreatic neoplasmII1NCT02465060
Prostatic NeoplasmsII1NCT02465060
Rectal neoplasmII1NCT02465060
Stomach neoplasmII1NCT02465060
Thyroid neoplasmII1NCT02465060
Transitional cell carcinomaII1NCT03047213
Uterine cervix neoplasmII1NCT02465060
Uterine neoplasmII1NCT02465060
Non-small-cell lung carcinomaI2NCT02503722
Brain NeoplasmsI1NCT04250545
Fallopian tube neoplasmI1NCT02142803
GlioblastomaI1NCT02142803
Meningeal neoplasmI1NCT04250545

Everything on Sapanisertib

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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