PhuturdexDrug Pipeline Intelligence

Phuturdex › Drugs › Pemetrexed

Drugs in development · updated 30 October 2026

Pemetrexed: clinical trials and development status

Other names and codes: Axtle, Pemfexy, Alimta

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 20 September 2004

As of 30 October 2026 Pemetrexed is in 323 active clinical trials (recruiting or ongoing, phases I–III) for 61 diseases. The most advanced phase is III.

323Active trials
IIIMost advanced phase
61Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Pemetrexed and get an email at every change or safety alert.

Sign in free →

Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 61 diseases.

DiseaseMost advanced phaseActive trialsReference trial
Non-small-cell lung carcinomaIII182NCT06623422
Lung neoplasmIII54NCT04267848
MetastasisIII19NCT06119581
NeoplasmIII16NCT03768063
Malignant mesotheliomaIII10NCT06097728
CarcinomaIII7NCT06417814
MesotheliomaIII7NCT06097728
Adenocarcinoma of the lungIII6NCT04339218
Ovarian neoplasmIII3NCT05059522
Uterine cervix neoplasmIII3NCT07797153
AdenocarcinomaIII2NCT06564844
Lung diseaseIII2NCT06119581
Bronchial neoplasmIII1NCT06119581
Carcinoma, BronchogenicIII1NCT06119581
Neoplastic ProcessesIII1NCT06119581
Respiratory diseaseIII1NCT06119581
Respiratory tract neoplasmIII1NCT06119581
Thoracic NeoplasmsIII1NCT06119581
Colorectal neoplasmI–II11NCT07020221
Meningeal carcinomatosisII11NCT05805631
MelanomaII7NCT07492680
Pancreatic neoplasmII7NCT07492680
Endometrial neoplasmI–II5NCT07020221
Brain NeoplasmsII4NCT07492680
Colonic neoplasmI–II4NCT07594626
Biliary tract neoplasmI–II3NCT07020221
CholangiocarcinomaI–II3NCT07020221
Head and neck squamous cell carcinomaI–II3NCT04083599
Transitional cell carcinomaII3NCT05335941
Esophageal neoplasmI–II2NCT07594626

Everything on Pemetrexed

In Phuturdex you get every trial with sponsors, countries and dates, development events, FDA and EMA approvals, patents and exclusivities, orphan designations and safety alerts, with PDF and Excel export. Free until 31 March 2027.

Open in Phuturdex →

Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

ItalianoFrançaisDeutsch