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Drugs in development · updated 30 October 2026

Izalontamab brengitecan: clinical trials and development status

Other names and codes: BL-B01D1, BMS-986507

FDA substance registryNot approved in the USNo EMA authorisationEstimated launch Dec 2027 – Oct 2028 (Phuturdex estimate)

As of 30 October 2026 Izalontamab brengitecan is in 55 active clinical trials (recruiting or ongoing, phases I–III) for 29 diseases. The most advanced phase is III.

55Active trials
IIIMost advanced phase
29Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Izalontamab brengitecan and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Non-small-cell lung carcinomaIII15NCT07640789
Lung small cell carcinomaIII6NCT07502300
Breast neoplasmIII5NCT07648914
Nasopharyngeal CarcinomaIII5NCT07783321
Triple-negative breast neoplasmIII5NCT07729956
Transitional cell carcinomaIII3NCT06857175
Esophageal squamous cell carcinomaIII2NCT06304974
Biliary tract neoplasmIII1NCT07582315
Fallopian tube neoplasmIII1NCT06994195
Ovarian epithelial carcinomaIII1NCT06994195
Uterine cervix neoplasmII4NCT07054567
Endometrial neoplasmII3NCT07054567
Esophageal neoplasmII3NCT06008054
Head and neck squamous cell carcinomaII3NCT06437522
Colorectal neoplasmII2NCT06008054
Ovarian neoplasmI–II2NCT05803018
Pancreatic neoplasmII2NCT07825753
Stomach neoplasmII2NCT06008054
ChordomaII1NCT06787664
GlioblastomaII1NCT06598787
Kidney neoplasmII1NCT06962787
Lung neoplasmI–II1NCT06618287
Urologic NeoplasmsII1NCT05785039
Bladder neoplasmI1NCT05393427
Digestive system neoplasmI1NCT05262491
Head and neck neoplasmsI1NCT05194982
MetastasisI1NCT05194982
Nasopharyngeal neoplasmI1NCT05983432
Renal cell carcinomaI1NCT05393427

Everything on Izalontamab brengitecan

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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