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Drugs in development · updated 30 October 2026

Disitamab Vedotin: clinical trials and development status

Other names and codes: RC48-ADC

NLM verified identityNot approved in the USNo EMA authorisationEstimated launch Dec 2027 – Oct 2028 (Phuturdex estimate)

As of 30 October 2026 Disitamab Vedotin is in 72 active clinical trials (recruiting or ongoing, phases I–III) for 19 diseases. The most advanced phase is III.

72Active trials
IIIMost advanced phase
19Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Disitamab Vedotin and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Breast neoplasmIII12NCT04400695
Stomach neoplasmIII10NCT07315750
Bladder neoplasmIII7NCT05911295
Transitional cell carcinomaIII4NCT05911295
Non-muscle invasive bladder neoplasmII5NCT06187506
Non-small-cell lung carcinomaII4NCT06003231
Extramammary Paget's diseaseII2NCT07117851
NeoplasmII2NCT07879469
Ovarian neoplasmII2NCT06540729
Triple-negative breast neoplasmII2NCT06649331
Biliary tract neoplasmII1NCT07159217
CarcinomaII1NCT05917158
Endometrial neoplasmII1NCT06003231
Head and neck neoplasmsII1NCT06003231
Lung neoplasmII1NCT06749860
Rectal neoplasmII1NCT07509424
Salivary gland neoplasmII1NCT06145308
Sebaceous adenocarcinomaII1NCT07740993
Uterine cervix neoplasmII1NCT06155396

Everything on Disitamab Vedotin

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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