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Drugs in development · updated 30 October 2026

Bupivacaine: clinical trials and development status

Other names and codes: Exparel, Sensorcaine, Xaracoll, Posimir, Marcaine, Marcaine Hydrochloride Preservative Free

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 24 September 2020

As of 30 October 2026 Bupivacaine is in 63 active clinical trials (recruiting or ongoing, phases I–III) for 40 diseases. The most advanced phase is III.

63Active trials
IIIMost advanced phase
40Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Bupivacaine and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 40 diseases.

DiseaseMost advanced phaseActive trialsReference trial
Postoperative painIII16NCT07878156
AgnosiaIII6NCT07663435
MigraineIII2NCT06937385
NephrolithiasisIII2NCT06349668
PainIII2NCT05964868
Atrial fibrillationIII1NCT07893275
Back painII–III1NCT06350981
Breast neoplasmIII1NCT03351348
Cleft palateIII1NCT04928352
Digestive System DiseasesIII1NCT03214510
Gender dysphoriaIII1NCT04979338
HeadacheIII1NCT06937385
Heart diseaseII–III1NCT06077422
HemorrhageII–III1NCT06456255
Infratentorial neoplasmIII1NCT07878156
Kidney neoplasmIII1NCT06349668
Lung neoplasmIII1NCT06810375
Paranasal sinus diseaseII–III1NCT06456255
Renal cell carcinomaIII1NCT07092566
Tension headacheIII1NCT06937385
Ureteral neoplasmIII1NCT06349668
Wrist FracturesIII1NCT06179004
Chronic painII1NCT07839195
Cluster headacheII1NCT04930887
Duodenal neoplasmII1NCT06411795
Facial neuralgiaII1NCT04930887
Facial painII1NCT04930887
Joint DiseasesII1NCT07839195
Pancreatic neoplasmII1NCT06411795
Paroxysmal hemicraniaII1NCT04930887

Everything on Bupivacaine

In Phuturdex you get every trial with sponsors, countries and dates, development events, FDA and EMA approvals, patents and exclusivities, orphan designations and safety alerts, with PDF and Excel export. Free until 31 March 2027.

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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