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Drugs in development · updated 30 October 2026

Paranasal sinus disease: drugs in development

As of 30 October 2026 there are 3 active clinical trials (recruiting or ongoing, phases I–III) on 3 drugs for paranasal sinus disease. One is experimental, that is not yet approved in the United States.

3Active trials
1Experimental drugs
1Experimental, in phase III

Summary updated every week · data as of 30 October 2026. In Phuturdex you get the full detail of every drug and an email when an alert is published on the ones you follow.

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Experimental drugs

Not yet approved by the US FDA for any indication.

DrugMost advanced phaseActive trialsReference trial
GSK5784283III2NCT07782970

Sorted by most advanced phase and number of active trials.

Approved drugs in new trials

Approved by the US FDA for at least one indication, not necessarily this disease, and now in active trials on it.

DrugMost advanced phaseActive trialsReference trial
BupivacaineExparel, BupivacainII–III1NCT06456255
EpinephrineAdrenaline, Adrenalin®II–III1NCT06456255

Sorted by most advanced phase and number of active trials.

All 3 drugs, with the details

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Source: Phuturdex analysis of ClinicalTrials.gov data (U.S. National Library of Medicine), updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III, with at least one identified drug; phase and sites refer to the trials on this disease. Disease name: Wikidata; NLM MeSH term: D010254 “Paranasal Sinus Diseases”.

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