PhuturdexDrug Pipeline Intelligence

Phuturdex › Drugs › Petosemtamab

Drugs in development · updated 30 October 2026

Petosemtamab: clinical trials and development status

Other names and codes: MCLA-158

FDA substance registryNot approved in the USNo EMA authorisationEstimated launch Mar 2029 – Jan 2030 (Phuturdex estimate)

As of 30 October 2026 Petosemtamab is in 5 active clinical trials (recruiting or ongoing, phases I–III) for 6 diseases. The most advanced phase is III.

5Active trials
IIIMost advanced phase
6Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Petosemtamab and get an email at every change or safety alert.

Sign in free →

Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov.

DiseaseMost advanced phaseActive trialsReference trial
Head and neck squamous cell carcinomaIII3NCT06496178
Colorectal neoplasmIII2NCT07775287
Head and neck neoplasmsIII1NCT06525220
Laryngeal diseaseIII1NCT06525220
Esophageal neoplasmI–II1NCT03526835
Stomach neoplasmI–II1NCT03526835

Everything on Petosemtamab

In Phuturdex you get every trial with sponsors, countries and dates, development events, FDA and EMA approvals, patents and exclusivities, orphan designations and safety alerts, with PDF and Excel export. Free until 31 March 2027.

Open in Phuturdex →

Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

ItalianoFrançaisDeutsch