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Drugs in development · updated 30 October 2026

Regorafenib: clinical trials and development status

Other names and codes: BAY73-4506, Stivarga

NLM verified identityApproved in the US (FDA)Authorised in the EU (EMA) since 26 August 2013

As of 30 October 2026 Regorafenib is in 72 active clinical trials (recruiting or ongoing, phases I–III) for 36 diseases. The most advanced phase is III.

72Active trials
IIIMost advanced phase
36Diseases studied

Summary updated every week · data as of 30 October 2026. In Phuturdex you can follow Regorafenib and get an email at every change or safety alert.

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Diseases studied

For each disease: the drug’s most advanced phase and active trials, with the reference trial on ClinicalTrials.gov. Showing 30 of 36 diseases.

DiseaseMost advanced phaseActive trialsReference trial
Colorectal neoplasmIII21NCT07730489
Hepatocellular carcinomaII–III12NCT07392866
Gastrointestinal stromal tumorII–III5NCT07379047
GlioblastomaII–III2NCT03970447
NeoplasmII4NCT03899155
Colonic neoplasmII2NCT07003022
Esophageal neoplasmII2NCT04757363
Liver neoplasmII2NCT05622136
Lung neoplasmII2NCT02955940
MelanomaII2NCT05370807
OsteosarcomaII2NCT04698785
AstrocytomaI–II1NCT06047379
Bone neoplasmII1NCT04698785
Brain NeoplasmsI–II1NCT06047379
Breast neoplasmII1NCT02955940
Central nervous system neoplasmI–II1NCT06047379
CholangiocarcinomaII1NCT06946849
Digestive system neoplasmII1NCT06099821
Esophageal squamous cell carcinomaI–II1NCT06047379
Head and neck squamous cell carcinomaI–II1NCT06047379
Hematologic neoplasmII1NCT05159245
Lung small cell carcinomaI–II1NCT06047379
MeningiomaII1NCT06275919
Merkel cell carcinomaI–II1NCT06047379
MetastasisII1NCT04116541
Non-small-cell lung carcinomaI–II1NCT06047379
Ovarian neoplasmII1NCT05113368
Pancreatic neoplasmII1NCT02955940
Rectal neoplasmII1NCT04503694
Renal cell carcinomaI–II1NCT06047379

Everything on Regorafenib

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Source: Phuturdex analysis of ClinicalTrials.gov (U.S. National Library of Medicine), FDA and EMA data, updated 30 October 2026. Active trials = recruiting or ongoing, phases I–III. Diseases are those named by each trial (NLM MeSH terms). The estimated launch, when shown, is a Phuturdex calculation described on the Method page, not official data.

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